Benzene, 1-ethynyl-3-nitro- → Benzenamine, 3-ethynyl-

Participants

Reaction Steps

Example 3 was repeated using 25 grams of 3-nitrophenylacetylene (10% wt. conc.) in methanol in the presence of 16.0 grams of a cobalt polysulfide catalyst prepared as per Example 1. The weight ratio of NPA to Co was 25:1. Reaction was carried out at 120° C., 1000 psig (6.9 MPa) of hydrogen pressure for 0.5 hours. Analysis showed quantitative conversion of feed and a 70% yield of 3-aminophenylacetylene. All byproducts were polymeric and easily separated. The results are summarized in Table 1 below.

Provenance & Evidence