HuagongsheHuagongshe Chemistry Print Report · For research reference only
N~1~-Benzyl-4-chlorobenzene-1,2-diamine → HCID 12891465, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N~1~-Benzyl-4-chlorobenzene-1,2-diamine | HCID 2385942 | — |
| Reactant | Ethyl 4-isothiocyanatopiperidine-1-carboxylate | HCID 3018454 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 12891465 | HCID 12891465 | 100% |
Reaction Steps
A mixture of 10.6 parts of ethyl 4-isothiocyanato-1-piperidinecarboxylate, 11.6 parts of 4-chloro-N1 -(phenylmethyl)-1,2-benzenediamine and 90 parts of tetrahydrofuran is stirred overnight at room temperature. The reaction mixture is evaporated, yielding 21 parts (100%) of ethyl 4-[{[{5-chloro-2-[(phenylmethyl)amino]phenyl}amino]thioxomethyl}amino]-1-piperidinecarboxylate; mp. 162° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04219559 |
| Source dataset | uspto-grants-1980_08 |
| ORD ID | ord-216b2999ad6c487aa610b0ae466c9bc8 |
| Source note | uspto-grants-1980_08 |