Piperidin-3-ylmethanol → HCID 22132366, compound

HRID 1856654Notes

Reaction equation

HRID 1856654 reaction equation
[OH:1][CH2:2][CH:3]1[CH2:8][CH2:7][CH2:6][NH:5][CH2:4]1.O=[C:10]1[CH2:15][CH2:14][N:13]([C:16]2[CH:23]=[CH:22][CH:21]=[CH:20][C:17]=2[C:18]#[N:19])[CH2:12][CH2:11]1>>[OH:1][CH2:2][CH:3]1[CH2:8][CH2:7][CH2:6][N:5]([CH:10]2[CH2:15][CH2:14][N:13]([C:16]3[CH:23]=[CH:22][CH:21]=[CH:20][C:17]=3[C:18]#[N:19])[CH2:12][CH2:11]2)[CH2:4]1

Participants

3

Reactant 2

HCID 107308Piperidin-3-ylmethanolHCID 15512646HCID 15512646, compound

Product 1

HCID 22132366HCID 22132366, compound

Procedure

The title compound was prepared from 21 (1.13 g, 5.6 mmol) and 5 (750 mg, 3.75 mmol) using the procedure described in 16 to give the title compound.

Sources & evidence

ORD record
ord-677a3354b9dd4bf3bfbccc930c0a6281
Source dataset
uspto-grants-2000_11
Patent number
US06143750

Reaction notes

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