Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 3-Iodo-N,N-dimethyl-2-pyridinamine | HCID 22132411 | — |
| Reactant | (1S,2R)-4-(2-hydroxy-1-methyl-4-pyridin-3-ylbutoxy)benzeneboronic acid | HCID 54413593 | — |
| Catalyst | HCID 178418397 | HCID 178418397 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 57183697 | HCID 57183697 | — |
Reaction Steps
Prepared according to the method described in Example 21b) from 3-iodo-2-dimethylaminopyridine (Example 23a), 0.253 g), ethanol (3 ml), 2M aqueous sodium carbonate (0.5 ml), (1S,2R)-4-(2-hydroxy-1-methyl-4-pyridin-3-ylbutoxy)benzeneboronic acid (Example 21a), 0.200 g), and tetrakis(triphenylphosphine)palladium(0) (0.02 g) with heating at 90° C. for 3 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06143751 |
|---|
| Source dataset | uspto-grants-2000_11 |
|---|
| ORD ID | ord-bf288847ef2540d9b24f4ff0c164ab96 |
|---|
| Source note | uspto-grants-2000_11 |
|---|
