化工社化工社 化学情報印刷レポート · 研究参考用
2-Ethoxy-5-nitropyridine → 6-Ethoxypyridin-3-amine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Ethoxy-5-nitropyridine | HCID 295864 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 6-Ethoxypyridin-3-amine | HCID 3040301 | 97.8% |
反応手順
A mixture of 2-ethoxy-5-nitropyridine (3.60 g) and 10% Pd/C (360 mg) in ethanol (40 mL) was placed in a Paar bottle and shaken under hydrogen (50 PSI) for 16 h. The mixture was filtered through Celite using dichloromethane and concentrated to give 2.892 g of 2-ethoxy-5-aminopyridine as a gold solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06143760 |
| 出典データセット | uspto-grants-2000_11 |
| ORD ID | ord-a79c690e4b8e4b06bc10bd32da86b88f |
| 出典メモ | uspto-grants-2000_11 |