HCID 9807911, compound → HCID 9870498, compound

HRID 1856822Notes

Reaction equation

HRID 1856822 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:8]2[C:17]3[C:12](=[C:13]([CH2:32][CH2:33][C:34]4C=CC=CC=4)[CH:14]=[C:15]([O:18][CH:19]([C:26]4[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=4)[CH2:20][N:21]4[CH:25]=[CH:24][N:23]=[CH:22]4)[CH:16]=3)[N:11]([CH3:40])[C:10](=[O:41])[CH:9]=2)[CH:5]=[CH:6][CH:7]=1.C(N1C(CCOC2C=C3C(=CC=2)N(C)C(=O)C=C3C2C=CC=C(Cl)C=2)=CN=C1)C1C=CC=CC=1.C(N1C(CCOC2C=C3C(=C(CCC)C=2)N(C)C(=O)C=C3C2C=CC=C(Cl)C=2)=CN=C1)C1C=CC=CC=1.C(N1C(CCOC2C=C3C(=C(CCC4C=CC=CC=4)C=2)N(C)C(=O)C=C3C2C=CC=C(Cl)C=2)=CN=C1)C1C=CC=CC=1.ClC1C=C(C2C3C(=C(CCC)C(OC(C4C=CC=CC=4)CN4C=CN=C4)=CC=3)N(C)C(=O)C=2)C=CC=1.ClC1C=C(C2C3C(=C(CCC4C=CC=CC=4)C(OC(C4C=CC=CC=4)CN4C=CN=C4)=CC=3)N(C)C(=O)C=2)C=CC=1.C(N1C(CCOC2C=C3C(C(C4C=CC=C(Cl)C=4)=CC(=O)N3C)=CC=2)=CN=C1)C1C=CC=CC=1.C(N1C(CCOC2C(CCC)=C3C(C(C4C=CC=C(Cl)C=4)=CC(=O)N3C)=CC=2)=CN=C1)C1C=CC=CC=1.C(N1C(CCOC2C(CCC3C=CC=CC=3)=C3C(C(C4C=CC=C(Cl)C=4)=CC(=O)N3C)=CC=2)=CN=C1)C1C=CC=CC=1.ClC1C=CC=CC=1C1C2C(=C(CCC)C(OC(C3C=CC=CC=3)CN3C=CN=C3)=CC=2)OC(=O)C=1.ClC1C=CC=CC=1C1C2C(=C(CCC3C=CC=CC=3)C(OC(C3C=CC=CC=3)CN3C=CN=C3)=CC=2)OC(=O)C=1.C(N1C(CCOC2C=C3C(C(C4C=CC=CC=4Cl)=CC(=O)O3)=CC=2)=CN=C1)C1C=CC=CC=1.C(N1C(CCOC2C(CCC)=C3C(C(C4C=CC=CC=4Cl)=CC(=O)O3)=CC=2)=CN=C1)C1C=CC=CC=1.C(N1C(CCOC2C(CCC3C=CC=CC=3)=C3C(C(C4C=CC=CC=4Cl)=CC(=O)O3)=CC=2)=CN=C1)C1C=CC=CC=1>>[Cl:1][C:2]1[CH:3]=[C:4]([C:8]2[C:17]3[C:12](=[C:13]([CH2:32][CH2:33][CH3:34])[CH:14]=[C:15]([O:18][CH:19]([C:26]4[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=4)[CH2:20][N:21]4[CH:25]=[CH:24][N:23]=[CH:22]4)[CH:16]=3)[N:11]([CH3:40])[C:10](=[O:41])[CH:9]=2)[CH:5]=[CH:6][CH:7]=1

Participants

15

Reactant 14

HCID 9807911HCID 9807911, compoundHCID 9826651HCID 9826651, compoundHCID 9829610HCID 9829610, compoundHCID 9849275HCID 9849275, compoundHCID 9850773HCID 9850773, compoundHCID 9870499HCID 9870499, compoundHCID 9870547HCID 9870547, compoundHCID 9872172HCID 9872172, compoundHCID 9890306HCID 9890306, compoundHCID 9890867HCID 9890867, compoundHCID 9894017HCID 9894017, compoundHCID 9914349HCID 9914349, compoundHCID 9916139HCID 9916139, compoundHCID 9934399HCID 9934399, compound

Product 1

HCID 9870498HCID 9870498, compound

Procedure

##STR11## 4-(3-Chloro-phenyl)-6-(2-imidazol-1-yl-1-phenyl-ethoxy)-1-methyl-8-phenethyl-1H-quinolin-2-one: ##STR12## 6-[2-(3-Benzyl-3H-imidazol-4-yl)-ethoxy]-4-(3-chloro-phenyl)-1-methyl-1H-quinolin-2-one: ##STR13## 6-[2-(3-Benzyl-3H-imidazol-4-yl)-ethoxy]-4-(3-chloro-phenyl)-1-methyl-8-propyl-1H-quinolin-2-one: ##STR14## 6-[2-(3-Benzyl-3H-imidazol-4-yl)-ethoxy]-4-(3-chloro-phenyl)-1-methyl-8-phenethyl-1H-quinolin-2-one: ##STR15## 4-(3-Chloro-phenyl)-7-(2-imidazol-1-yl-1-phenyl-ethoxy)-1-methyl-8-propyl-1H-quinolin-2-one: ##STR16## 4-(3-Chloro-phenyl)-7-(2-imidazol-1-yl-1-phenyl-ethoxy)-1-methyl-8-phenethyl-1H-quinolin-2-one: ##STR17## 7-[2-(3-Benzyl-3H-imidazol-4-yl)-ethoxy]-4-(3-chloro-phenyl)-1-methyl-1H-quinolin-2-one: ##STR18## 7-[2-(3-Benzyl-3H-imidazol-4-yl)-ethoxy]-4-(3-chloro-phenyl)-1-methyl-8-propyl-1H-quinolin-2-one: ##STR19## 7-[2-(3-Benzyl-3H-imidazol-4-yl)-ethoxy]-4-(3-chloro-phenyl)-1-methyl-8-phenethyl-1H-quinolin-2-one: ##STR20## 4-(2-Chloro-phenyl)-7-(2-imidazol-1-yl-1-phenyl-ethoxy)-8-propyl-chromen-2-one: ##STR21## 4-(2-Chloro-phenyl)-7-(2-imidazol-1-yl-1-phenyl-ethoxy)-8-phenethyl-chromen-2-one: ##STR22## 7-[2-(3-Benzyl-3H-imidazol-4-yl)-ethoxy]-4-(2-chloro-phenyl)-chromen-2-one: ##STR23## 7-[2-(3-Benzyl-3H-imidazol-4-yl)-ethoxy]-4-(2-chloro-phenyl)-8-propyl-chromen-2-one: ##STR24## 7-[2-(3-Benzyl-3H-imidazol-4-yl)-ethoxy]-4-(2-chloro-phenyl)-8-phenethyl-chromen-2-one: ##STR25##

Sources & evidence

ORD record
ord-6de60385bb394b918d633f56a971404d
Source dataset
uspto-grants-2000_11
Patent number
US06143766

Reaction notes

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