反应详情

Methyl 4-(3-chlorocarbonyl-4,5,6,7-tetrahydrobenzo[b]thiophen-2-ylcarbamoyl)benzoate is added to a solution of (benzo[1,3]dioxol-5-ylmethyl)amine in dichloromethane and 1.1 equivalents of pyridine and the solution is stirred. The solvent is removed and is worked up in a customary manner. 1.3 g of methyl 4-{3[(benzo[1,3]dioxol-5-ylmethyl)carbamoyl]-4,5,6,7-tetrahydrobenzo[b]thiophene-2-ylcarbamoyl}benzoate, m.p. 165°, are obtained.

1. customThe solvent is removed