Ethyl 5-bromovalerate → HCID 53850299, compound

HRID 1856854Notes

Reaction equation

HRID 1856854 reaction equation
[Cl:1][C:2]1[C:3]([CH2:11][N:12]2[C:16]([C:17]([O:19][CH2:20][CH3:21])=[O:18])=[C:15]([SH:22])[N:14]=[C:13]2[CH2:23][CH2:24][CH3:25])=[CH:4][C:5]2[O:9][CH2:8][O:7][C:6]=2[CH:10]=1.Br[CH2:27][CH2:28][CH2:29][CH2:30][C:31]([O:33][CH2:34][CH3:35])=[O:32]>>[Cl:1][C:2]1[C:3]([CH2:11][N:12]2[C:16]([C:17]([O:19][CH2:20][CH3:21])=[O:18])=[C:15]([S:22][CH2:27][CH2:28][CH2:29][CH2:30][C:31]([O:33][CH2:34][CH3:35])=[O:32])[N:14]=[C:13]2[CH2:23][CH2:24][CH3:25])=[CH:4][C:5]2[O:9][CH2:8][O:7][C:6]=2[CH:10]=1

Participants

3

Reactant 2

HCID 84580Ethyl 5-bromovalerateHCID 19609113HCID 19609113, compound

Product 1

HCID 53850299HCID 53850299, compound

Procedure

The operation is carried out as in Stage 7 of Example 1 starting with the product obtained in Stage 6 of Example 1 and ethyl 5-bromo-pentanoate instead of ethyl 4-bromocyclohexaneacetate. In this way the expected product is obtained.

Sources & evidence

ORD record
ord-079c2d4b60d94f1883c520b857beb1a1
Source dataset
uspto-grants-2000_11
Patent number
US06143774

Reaction notes

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