2-(3-Methoxy-4-(methoxycarbonyl)phenyl)acetic acid → Methyl 2-methoxy-4-[N-(alpha-phenyl-2-piperidino-benzyl)aminocarbonylmethyl]-benzoate
Reaction equation
[C:1]1([CH:7]([NH2:20])[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=2[N:14]2[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:21][O:22][C:23]1[CH:24]=[C:25]([CH2:33][C:34](O)=[O:35])[CH:26]=[CH:27][C:28]=1[C:29]([O:31][CH3:32])=[O:30]>>[CH3:21][O:22][C:23]1[CH:24]=[C:25]([CH2:33][C:34]([NH:20][CH:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=2[N:14]2[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]2)=[O:35])[CH:26]=[CH:27][C:28]=1[C:29]([O:31][CH3:32])=[O:30]Participants
3
Procedure
Prepared from α-phenyl-2-piperidino-benzylamine and 3-methoxy-4-methoxycarbonyl-phenylacetic acid.
Sources & evidence
- ORD record
- ord-135ef2dd149f4c8ca6e310a041ce6b61
- Source dataset
- uspto-grants-2000_11
- Patent number
- US06143769
Reaction notes
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