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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1856987Generated: October 31, 2026

2-Bromopropane → Ethyl 2-isopropoxy-4-[N-{1-(2-piperidino-phenyl)-1-butyl}aminocarbonylmethyl]-benzoate

https://huagongshe.com/reaction/1856987

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-BromopropaneHCID 6358—
Reactantethyl 2-hydroxy-4-[N-{1-(2-piperidinophenyl)-1-butyl}-aminocarbonylmethyl]-benzoateHCID 15227812—
ProductEthyl 2-isopropoxy-4-[N-{1-(2-piperidino-phenyl)-1-butyl}aminocarbonylmethyl]-benzoateHCID 21261827—

Reaction Steps

Prepared from ethyl 2-hydroxy-4-[N-{1-(2-piperidino-phenyl)-1-butyl}-aminocarbonylmethyl]-benzoate, using 1.5 equivalents of isopropyl bromide at 150° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06143769
Source datasetuspto-grants-2000_11
ORD IDord-0dba29426c51446681c20a1fcd8bf9fa
Source noteuspto-grants-2000_11