Sodium Carbonate → Solketal

Participants

Reaction Conditions

Reaction Steps

Then sodium carbonate (32.22 g, 0.304 mol) was added to a mixture of the crude 4-benzoyloxymethyl-2,2-dimethyl-1,3-dioxolane (48.06 g, 0.203 mol) and water (100 ml) resulting mixture was stirred for 8 hours at 100° C. After cooling the reaction mixture was extracted with methylene chloride. The extract was washed with saturated brine, dried over anhydrous sodium sulfate and condensed in vacuo. The crude product was distilled to give 22.03 g of 2,2-dimethyl-1,3-dioxolane-4-methanol (yield 82%, b.p. 72° C. at 8 mmHg).

Provenance & Evidence