Sodium Carbonate → Solketal

Participants

Reaction Conditions

Reaction Steps

Then sodium carbonate (40.63 g, 0.294 mol) was added to a mixture of 4-acetoxymethyl-2,2-dimethyl-1,3-dioxolane (34.18 g, 0.196 mol) and methanol (200 ml) and the resulting mixture was stirred for 8 hours at 25° C. After completion of the reaction the salt was filtered off and the filtrate was condensed in vacuo and water was added to the residue and extracted with methylene chloride. The extract was washed with saturated brine, dried over anhydrous sodium sulfate and condensed in vacuo. The crude product was distilled to give 23.12 g of 2,2-dimethyl-1,3-dioxolane-4-methanol (yield 89%, b.p. 72° C. at 8 mmHg).

Provenance & Evidence