Sodium Carbonate → Solketal

Participants

Reaction Conditions

Reaction Steps

Sodium carbonate (16.53 g, 0.156 mol) was added to a mixture of the crude 4-benzoyloxymethyl-2,2-dimethyl-1,3-dioxolane (24.63 g, 0.104 mol) and water (50 ml) and resulting mixture was stirred for 8 hours at 100° C. After cooling the mixture was extracted with methylene chloride. The extract was washed with saturated brine, dried over anhydrous sodium sulfate and condensed in vacuo. The residue was distilled to give 10.86 g of 2,2-dimethyl-1,3-dioxolane-4-methanol (yield 79%, b.p. 68° C. at 6 mmHg).

Provenance & Evidence