HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1857100Generated: November 3, 2026
4-Chloro-6,7-dimethoxyquinoline → 6,7-Dimethoxy-4-(5-methoxy-1-naphthyloxy)quinoline
https://huagongshe.com/reaction/1857100
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Chloro-6,7-dimethoxyquinoline | HCID 459610 | — |
| Reactant | 5-Methoxynaphthalen-1-ol | HCID 11062901 | — |
| Product | 6,7-Dimethoxy-4-(5-methoxy-1-naphthyloxy)quinoline | HCID 22132778 | 14% |
Reaction Steps
4-Chloro-6,7-dimethoxyquinoline (85 mg) and 5-methoxy-1-naphthol (67 mg) obtained in Example 5 were mixed and stirred at 180° C. for 20 minutes, and the reaction mixture was then purified in the same manner as described in Example 2 to obtain 19 mg of the title compound (yield: 14%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06143764 |
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| Source dataset | uspto-grants-2000_11 |
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| ORD ID | ord-5bd379ee80b24fbb9d72f421508f3f0d |
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| Source note | uspto-grants-2000_11 |
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