HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorophenyl isocyanate → HCID 11270447, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorophenyl isocyanate | HCID 70955 | — |
| Reactant | 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline | HCID 11594543 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 11270447 | HCID 11270447 | 48% |
Reaction Steps
6,7-Dimethoxy-4-(4-aminophenoxy)quinoline (54 mg) was dissolved in toluene (3 ml) with heat, 4-fluorophenyl isocyanate (0.2 ml) was added, and the admixture was refluxed with heat for 70 minutes. The separated crystals were filtered and washed with toluene to obtain 38 mg of the title compound (yield: 48%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06143764 |
| Source dataset | uspto-grants-2000_11 |
| ORD ID | ord-2f0a750a44db41aea9d4ad63729a641d |
| Source note | uspto-grants-2000_11 |