HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromophenyl isocyanate → HCID 22132663, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromophenyl isocyanate | HCID 75609 | — |
| Reactant | 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline | HCID 11594543 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 22132663 | HCID 22132663 | 64% |
Reaction Steps
6,7-Dimethoxy-4-(4-aminophenoxy)quinoline (52 mg) was dissolved in toluene (3 ml) with heat, 4-bromophenyl isocyanate (0.2 ml) was added, and the admixture was refluxed with heat for 50 minutes. The separated crystals were filtered and washed with toluene to obtain 56 mg of the title compound (yield: 64%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06143764 |
| Source dataset | uspto-grants-2000_11 |
| ORD ID | ord-97c12e79e6664830b2476545923aebb0 |
| Source note | uspto-grants-2000_11 |