HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Phenoxyphenyl isocyanate → HCID 22132717, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Phenoxyphenyl isocyanate | HCID 2734896 | — |
| Reactant | 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline | HCID 11594543 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 22132717 | HCID 22132717 | 60% |
Reaction Steps
6,7-Dimethoxy-4-(4-aminophenoxy)quinoline (53 mg) was dissolved in toluene (3 ml) with heat, 4-phenoxyphenyl isocyanate (0.2 ml) was added, and the admixture was refluxed with heat for 30 minutes. The resulting residue was purified by column chromatography on silica gel eluting with chloroform/acetone (10/1) to obtain 55 mg of the title compound (yield: 60%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06143764 |
| Source dataset | uspto-grants-2000_11 |
| ORD ID | ord-e30cfb7d1a414eb2b1bbdeb40f6bf7e8 |
| Source note | uspto-grants-2000_11 |