o-Isopropylphenyl isocyanate → HCID 22132744, compound

Participants

Reaction Steps

6,7-Dimethoxy-4-(4-aminophenoxy)quinoline (44 mg) was dissolved in toluene (5 ml) with heat, 2-isopropylphenyl isocyanate (0.2 ml) was added, and the admixture was refluxed with heat for 80 minutes. The resulting residue was purified by column chromatography on silica gel eluting with chloroform/acetone (10/1) to obtain 14 mg of the title compound (yield: 20%).

Provenance & Evidence