Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Anisole | HCID 7519 | — |
| Reactant | 2-Methylbenzoyl chloride | HCID 70276 | — |
| Reactant | Ytterbium triflate | HCID 2733225 | — |
| Solvent | Nitromethane | HCID 6375 | — |
| Product | 4-METHOXY-2'-METHYLBENZOPHENONE | HCID 614521 | 74.2% |
Reaction Steps
To commercially available nitromethane (10 ml) were added commercially available anisole (1.081 g), commercially available 2-methylbenzoyl chloride (1.546 g) and commercially available ytterbium(III) trifluoromethanesulfonate (620 mg), and the admixture was stirred at 60° C. for 7 hours. The reaction mixture was treated in the same manner as described in Example 120 to obtain 1.679 g of the title compound (yield: 74%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06143764 |
|---|
| Source dataset | uspto-grants-2000_11 |
|---|
| ORD ID | ord-0410269a9d474fa1a311624fa476872d |
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| Source note | uspto-grants-2000_11 |
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