(4-Methoxyphenyl)(3-methylphenyl)methanone → (4-Hydroxyphenyl)(3-methylphenyl)methanone

Participants

Reaction Steps

4-Methoxyphenyl 3-methylphenyl ketone (603 mg) obtained in Example 131 was dissolved in dichloromethane (3 ml), a 1.0 M boron tribromide-dichloromethane solution (11 ml) was added while cooled in ice, and the admixture was stirred at room temperature for 22 hours, after which the reaction mixture was treated in the same manner as described in Example 121 to obtain 316 mg of the title compound (yield: 56%).

Provenance & Evidence