4-Chloro-6,7-dimethoxyquinoline → HCID 22132757, compound

Participants

Reaction Steps

Under argon, 4-hydroxyphenyl 3, 4-methylenedioxyphenyl ketone (202 mg) obtained in Example 136 and 4-dimethylaminopyridine (112 mg) were added to xylene (2 ml), and the admixture was stirred at room temperature for 1 hour. 4-Chloro-6,7-dimethoxyquinoline (187 mg) was added, and the admixture was refluxed with heat for 20 hours. The reaction mixture was treated in the same manner as described in Example 124 to obtain 135 mg of the title compound (yield: 38%).

Provenance & Evidence