HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium methanethiolate → 4-n-Butylphenyl 4-hydroxyphenyl ketone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium methanethiolate | HCID 4378561 | — |
| Reactant | (4-Butylphenyl)(4-methoxyphenyl)methanone | HCID 12343545 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 4-n-Butylphenyl 4-hydroxyphenyl ketone | HCID 22132679 | 96.2% |
Reaction Steps
4-n-Butylphenyl 4-methoxyphenyl ketone (863 mg) obtained in Example 147 was dissolved in N,N-dimethylformamide (50 ml), sodium thiomethoxide (563 mg) was added, and the admixture was refluxed with heat for 7 hours under argon. The reaction mixture was treated in the same manner as described in Example 33 to obtain 787 mg of the title compound (yield: 96%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06143764 |
| Source dataset | uspto-grants-2000_11 |
| ORD ID | ord-7ccfce32019f4a41b56cdceeadb6b3b9 |
| Source note | uspto-grants-2000_11 |