HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Tert-Butylaniline → HCID 22132719, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Tert-Butylaniline | HCID 69861 | — |
| Reactant | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Reactant | HCID 22132796 | HCID 22132796 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 22132719 | HCID 22132719 | 38.3% |
Reaction Steps
4-[6,7-Dimethoxy-4-quinolyl)oxybenzoic acid (54 mg) and commercially available 4-tert-butylaniline (102 mg) were dissolved in N,N-dimethylformamide (3 ml), 1-ethyl-3-(3'-dimethylaminopropyl)carbodiimide hydrochloride (106 mg) was added, and the admixture was stirred at room temperature for 6 hours, after which the reaction mixture was purified in the same manner as described in Example 51 to obtain 29 mg of the title compound (yield: 35%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06143764 |
| Source dataset | uspto-grants-2000_11 |
| ORD ID | ord-9db229f31cdd4c70a6e3a6f6a46b894b |
| Source note | uspto-grants-2000_11 |