反应详情

6,7-Dimethoxy-4-(4-aminophenoxy)quinoline (104 mg) was dissolved in toluene (10 ml) with heat, 2-chloro-4-nitrophenyl isocyanate (150 mg) was added, and the admixture was refluxed with heat for 10 minutes. The separated crystals were filtered and then washed with toluene to obtain 172 mg of the title compound (yield: 100%).

1. temperaturewith heat
2. temperaturethe admixture was refluxed
3. temperaturewith heat for 10 minutes
4. filtrationThe separated crystals were filtered
5. washwashed with toluene