HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isocyanic Acid 4-Chloro-3-nitrophenyl Ester → HCID 22132678, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isocyanic Acid 4-Chloro-3-nitrophenyl Ester | HCID 142448 | — |
| Reactant | 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline | HCID 11594543 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 22132678 | HCID 22132678 | 143.9% |
Reaction Steps
6,7-Dimethoxy-4-(4-aminophenoxy)quinoline (52 mg) was dissolved in toluene (5 ml) with heat, 4-chloro-3-nitrophenyl isocyanate (224 mg) was added, and the admixture was refluxed with heat for 8 minutes. The separated crystals were filtered and then washed with toluene to obtain 125 mg of the title compound (yield: 75%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06143764 |
| Source dataset | uspto-grants-2000_11 |
| ORD ID | ord-47d8a3ffca7f4eed9362b1f8ff70d6f8 |
| Source note | uspto-grants-2000_11 |