Thiophenol → HCID 15480823, compound

Participants

Reaction Steps

THIOPHENOL (1.28 ML, 12.5 MMOL) WAS ADDED DROPWISE TO A STIRRED SOLUTION OF TRIETHYLAMINE (3.0 ML, 21.5 MMOL) AND 6-BROMOMETHYL-3-CHLORO-1-ETHOXYCARBONYLMETHYLPYRAZINONE (3.86 G, 12.5 MMOL) IN METHYLENE CHLORIDE (20 ML). AFTER 15 MIN THE MIXTURE WAS PARTITIONED BETWEEN METHYLENE CHLORIDE AND WATER. THE ORGANIC LAYER WAS DRIED (NA2SO4) AND EVAPORATED IN VACUO TO GIVE THE TITLE COMPOUND AS A CRYSTALLINE SOLID WHICH WAS CARRIED FORWARD TO THE NEXT STEP:

Provenance & Evidence