Trifluoroacetic acid → HCID 44587843, compound

Participants

Reaction Steps

To a solution of 65 mg (0.14 mmol) of the compound (14) in chloroform (2 ml) was added 2 ml of trifluoroacetic acid, and then the mixture was stirred at room temperature for 20 hours. The solvent was distilled off and the residue was subjected to column chromatography on ion exchange resin (Dowex 50Wx4) and washed with water, then eluted with 1N aqueous ammonia to give 23 mg of the title compound (15) (yield 65%).

Provenance & Evidence