HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → N-(4-chlorophenyl)-N'-2-butanesulfonylurea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | 4-Chlorophenyl Isocyanate | HCID 7693 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | Butane-2-sulfonamide | HCID 20482438 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | N-(4-chlorophenyl)-N'-2-butanesulfonylurea | HCID 9838965 | 18.6% |
Reaction Steps
The method of Example 10 was followed with 2-butanesulfonamide (6.85 g), methanol (250 ml), sodium methoxide (2.7 g), tetrahydrofuran (250 ml) and 4-chlorophenyl isocyanate (7.7 g) with the resulting solid being recrystallized from ethyl acetate to give 2.7 g of white crystals with a melting point of 172-174° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06147115 |
| Source dataset | uspto-grants-2000_11 |
| ORD ID | ord-c50f05fc12104693b6622508876bf68a |
| Source note | uspto-grants-2000_11 |