反应详情

To a solution of (3,5-dimethylphenyl)acetyl chloride (2.58 g in 20 mL dry dichloroethane) was added 2.5 g 2-amino-4-chlorobenzoic acid methyl ester and the mixture heated to reflux on an oil bath. After 2 hours, the pot was cooled to room temperature and the solvent removed in vacuo. Recrystallization of the crude product from methanol gave the title compound (4.05 g).

1. temperaturethe mixture heated
2. temperatureto reflux on an oil bath
3. customthe solvent removed in vacuo
4. customRecrystallization of the crude product from methanol