HCID 22130564, compound → {5-[(3-Chlorophenyl)sulfanyl]-1-methyl-4-(propan-2-yl)-1H-imidazol-2-yl}methanol

HRID 1857700Notes

Reaction equation

HRID 1857700 reaction equation
F[C:2]1C=C(SC2N(CC3C=CC=CN=3)C(CCC(OC)=O)=NC=2C(C)C)C=C(F)C=1.[Cl:31][C:32]1[CH:33]=[C:34]([S:38][C:39]2[NH:43][C:42]([CH2:44][O:45]CC3C=CC(OC)=CC=3)=[N:41][C:40]=2[CH:55]([CH3:57])[CH3:56])[CH:35]=[CH:36][CH:37]=1>>[Cl:31][C:32]1[CH:33]=[C:34]([S:38][C:39]2[N:43]([CH3:2])[C:42]([CH2:44][OH:45])=[N:41][C:40]=2[CH:55]([CH3:56])[CH3:57])[CH:35]=[CH:36][CH:37]=1

Participants

3

Reactant 2

HCID 22130564HCID 22130564, compoundHCID 178491400HCID 178491400, compound

Product 1

HCID 473921{5-[(3-Chlorophenyl)sulfanyl]-1-methyl-4-(propan-2-yl)-1H-imidazol-2-yl}methanol

Procedure

By the same procedures as in Reference Example 2 (1) through (4), 5-(3-chlorophenylthio)-4-isopropyl-2-(p-methoxybenzyloxymethyl)-1H-imidazole (16c) was obtained.

Sources & evidence

ORD record
ord-b327ffa151ea49a998151899dff84556
Source dataset
uspto-grants-2000_11
Patent number
US06147097

Reaction notes

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