化工社化工社 化学情報印刷レポート · 研究参考用
2-Azidomethyl-4-(3,5-difluorophenylthio)-1-ethyl-5-isopropyl-1h-imidazole → 1-[5-(3,5-Dichlorophenylthio)-2-hydroxymethyl-4-isopropyl-imidazol-1-yl]-propan-2-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Azidomethyl-4-(3,5-difluorophenylthio)-1-ethyl-5-isopropyl-1h-imidazole | HCID 22130337 | — |
| 反応物 | 1-acetylmethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-2-(p-methoxybenzyloxymethyl)-1H-imidazole | HCID 22130987 | — |
| 生成物 | 1-[5-(3,5-Dichlorophenylthio)-2-hydroxymethyl-4-isopropyl-imidazol-1-yl]-propan-2-one | HCID 473940 | — |
反応手順
Compound I-32 was obtained from 1-acetylmethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-2-(p-methoxybenzyloxymethyl)-1H-imidazole (17v) by the same synthetic process as that for Compound I-16 in Example 16 (yield 45%). mp 165-167° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06147097 |
| 出典データセット | uspto-grants-2000_11 |
| ORD ID | ord-d8ee87aabd8340d799063a89c3c61eed |
| 出典メモ | uspto-grants-2000_11 |