HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromothiophene-2-carbaldehyde → 4-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-2-thiophenecarboxaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromothiophene-2-carbaldehyde | HCID 87792 | — |
| Reactant | (5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)boronic acid | HCID 10353857 | — |
| Product | 4-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-2-thiophenecarboxaldehyde | HCID 18672507 | — |
Reaction Steps
In a similar manner to Example 3(b), by reaction of 4.3 g (18.7 mmol) of 5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthylboronic acid with 2.36 g (12.3 mmol) of 4-bromo-2-thiophenecarboxaldehyde, 2.3 g (63%) of the expected aldehyde derivative are obtained, with a melting point of 84-5° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06147255 |
| Source dataset | uspto-grants-2000_11 |
| ORD ID | ord-557cf4e6289c463f981384217305809f |
| Source note | uspto-grants-2000_11 |