HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → 4-bromo-1-methyl-1H-pyrrole-2-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | 4-Bromo-1H-pyrrole-2-carbaldehyde | HCID 599627 | — |
| Product | 4-bromo-1-methyl-1H-pyrrole-2-carbaldehyde | HCID 12196701 | 53.2% |
Reaction Steps
In a similar manner to Example 10(b), by reaction of 4 g (23 mmol) of 4-bromo-2-pyrrolecarboxaldehyde with 1.7 ml (27.6 mmol) of iodomethane, 2.3 g (50%) of the expected product are obtained, with a melting point of 123-4° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06147255 |
| Source dataset | uspto-grants-2000_11 |
| ORD ID | ord-9ee217683ad440a9af99012fab5e6718 |
| Source note | uspto-grants-2000_11 |