HCID 9820545, compound → HCID 9906514, compound

HRID 1857889Notes

Reaction equation

HRID 1857889 reaction equation
C[C:2]1[C:3]([C:16]2([CH2:19]/[CH:20]=[CH:21]/[C:22](/[CH3:27])=[CH:23]/[C:24]([OH:26])=[O:25])[CH2:18][CH2:17]2)=[CH:4][C:5]2[C:6]([CH3:15])([CH3:14])[CH2:7][CH2:8][C:9]([CH3:13])([CH3:12])[C:10]=2[CH:11]=1.CC1(C)CCC(C)(C)C2C=C(C3(C/C=C/C(/C)=C/C(O)=O)CC3)C(OC)=CC1=2.CC1(C)CCC(C)(C)C2C=C(C3(C/C=C/C(/C)=C/C(O)=O)CC3)C(OCC)=CC1=2.C(C1C=C(C2(C/C=C/C(/C)=C/C(O)=O)CC2)C=C(C(C)(C)C)C=1)(C)(C)C.C(C1C=C(C2(C/C=C/C(/C)=C/C(O)=O)CC2)C=CC=1CC)C.C(C1C=C2C(CCC2(C)C)=C(C2(C/C=C/C(/C)=C/C(O)=O)CC2)C=1)(C)(C)C.CC1(C)CCC(C)(C)C2C=C(C3(C/C=C/C(/C)=C/C(O)=O)CCCC3)C=CC1=2>>[CH3:12][C:9]1([CH3:13])[CH2:8][CH2:7][C:6]([CH3:14])([CH3:15])[C:5]2[CH:4]=[C:3]([C:16]3([CH2:19]/[CH:20]=[CH:21]/[C:22](/[CH3:27])=[CH:23]/[C:24]([OH:26])=[O:25])[CH2:17][CH2:18]3)[CH:2]=[CH:11][C:10]1=2

Participants

8

Reactant 7

HCID 9820545HCID 9820545, compound2×HCID 9820546HCID 9820546, compound2×HCID 9821348HCID 9821348, compound2×HCID 9884959HCID 9884959, compound2×HCID 9904354HCID 9904354, compound2×HCID 9907909HCID 9907909, compound2×HCID 86756042HCID 86756042, compound2×

Product 1

HCID 9906514HCID 9906514, compound

Procedure

(2E, 4E)-6-[(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl) cyclopropan-1-yl]-3-methyl hexadienoic acid (Compound 102); (2E, 4E)-6-[(5,5,8,8-tetramethyl-3-methoxy-5,6, 7,8-tetrahydronaphthalen-2-yl) cyclopropan-1-yl]-3-methyl hexadienoic acid (Compound 103); (2E, 4E)-6-[(5,5,8,8-tetramethyl-3-ethoxy-5,6, 7,8-tetrahydronaphthalen-2-yl) cyclopropan-1-yl]-3-methyl hexadienoic acid (Compound 104); (2E, 4E)-6-[(3,5-di-t-butyl phenyl) cyclopropan-1-yl]-3-methyl hexadienoic acid (Compound 105); (2E, 4E)-6-[(3,4-diethyl phenyl) cyclopropan-1-yl]-3-methyl hexadienoic acid (Compound 106); (2E, 4E)-6-[1-(6-t-butyl-1,1-dimethyl-indan-4-yl)-cyclopropyl]-3-methyl hexadienoic acid (Compound 107); and (2E, 4E)-6-[(5,5,8,8-tetramethyl-5,6, 7,8-tetrahydronaphthalen-2-yl) cyclopentane-1-yl]-3-methyl hexadienoic acid (Compound 108)

Sources & evidence

ORD record
ord-d51344417770410faf306941e47f21a5
Source dataset
uspto-grants-2000_11
Patent number
US06147224

Reaction notes

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