Hydrochloric Acid → HCID 22125743, compound

Participants

Reaction Conditions

Reaction Steps

Pyridine (16 ml) and concentrated hydrochloride acid (16.6 ml) were heated at 150° C. until the evaporation of water was ceased. 3-(2,6-Dinitro-3-hydroxy-4-methoxyphenyl)propanoic acid (2.3 g) was added and the resulting mixture heated at reflux for two minutes. The product mixture was cooled to about 150° C. and poured to ice water. The mixture was extracted with ethyl acetate and the product finally recrystallized from acetic acid. Yield: 0.93 g, melting point 165-166° C. NMR-data identical to that of example 11.

Provenance & Evidence