Cyclooctylamine → N-Cyclohexyl-N′-cyclooctylurea

Participants

Reaction Steps

Cyclooctylamine, 0.382 g (3.00 mmol), 0.40 mL (0.39 g, 3.1 mmol) of cyclohexylisocyanate in 20 mL of hexane, on standing for one day provides 0.664 g (88%) of 1-cyclohexyl-3-cyclooctylurea as white needles, mp 194.0-194.5° C. An infrared spectrum [3344 (s, NH), 3334 (s, NH), 1624 (vs, C=O), 1564 (vs. amide II) cm-1 ] and mass spectrum [FAB-MS m/z calcd. for C15H28N2O: 252, obsd: 253 (M+H+)] confirms the identity of this material.

Provenance & Evidence