1-Methyl-4-piperidone → HCID 15491456, compound

HRID 1858162Notes

Reaction equation

HRID 1858162 reaction equation
[OH:1][N:2]1[C:10]2[C:5](=[N:6][C:7]([NH2:11])=[CH:8][CH:9]=2)[CH:4]=[CH:3]1.[CH3:12][N:13]1[CH2:18][CH2:17][C:16](=O)[CH2:15][CH2:14]1>>[OH:1][N:2]1[C:10]2[C:5](=[N:6][C:7]([NH2:11])=[CH:8][CH:9]=2)[C:4]([C:16]2[CH2:17][CH2:18][N:13]([CH3:12])[CH2:14][CH:15]=2)=[CH:3]1

Participants

3

Reactant 2

HCID 740491-Methyl-4-piperidoneHCID 10154130HCID 10154130, compound

Product 1

HCID 15491456HCID 15491456, compound

Procedure

condensing 1-hydroxy-5-aminopyrrolo[3,2-b ]-pyridine (G) with 1-methyl-4-piperidinone in the presence of a base to provide 1-hydroxy-5-amino-3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)pyrrolo[3,2-b]pyridine (H); and

Sources & evidence

ORD record
ord-8cf5283ba8e840019eaee3794d9be215
Source dataset
uspto-grants-2000_11
Patent number
US06150525

Reaction notes

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