HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-5-(chloromethyl)pyridine → 2-Chloro-5-methyl-pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-5-(chloromethyl)pyridine | HCID 155479 | — |
| Reactant | 2-Chloro-5-(dichloromethyl)pyridine | HCID 594879 | — |
| Product | 2-Chloro-5-methyl-pyridine | HCID 581393 | — |
| Product | 2-Chloro-5-(dichloromethyl)pyridine | HCID 594879 | — |
Reaction Steps
The present invention relates to the preparation of 5-aminomethyl-2-chloropyridines by reacting a mixture of 5-chloromethyl-2-chloropyridine and 5-dichloromethyl-2-chloropyridine with substituted amines. The mixture of 5-chloromethyl-2-chloropyridine and 5-dichloromethyl-2-chloropyridine is obtained by chlorination of the 5-methyl-2-chloropyridine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06150528 |
| Source dataset | uspto-grants-2000_11 |
| ORD ID | ord-4301720d52e74943a1cfc51b7a973ca3 |
| Source note | uspto-grants-2000_11 |