HCID 10983066, compound → HCID 54547297, compound

Participants

Reaction Steps

6α-((4-Acetyloxy-butyl)-oxy)-4,5α-epoxy-17-methyl-morphinan-7-en-3-ol acetate (0.288 g, 0.63 mmol) in MeOH (30 ml) mixed with 10% Pd on 0.2 g) and then agitated for 1 hour at RT under H2 (1 bar over pressure). The catalyst is removed by filtering through a filter compound and the filtrate is concentrated by rotary evaporation. The residue obtained is purified by flash chromatography (20 g silica gel; mobile phase: CH2Cl2 /MeOH=9/1). The product is dissolved in glacial acetic acid and lyophilised.

Provenance & Evidence