Hydrochloric Acid → 1-Phenylethanol

Participants

Reaction Steps

2-Propanol (1.53 ml, 20 mmol) was added to 9.9 ml (10 mmol) of a toluene solution of DIBAH (1.02 M) at room temperature and the mixture was stirred at room temperature for 1 hour. Thereto was added 0.601 g of acetophenone, and the resultant mixture was stirred at room temperature for 6 hours, followed by hydrolysis with 1 N hydrochloric acid with ice cooling. Extraction with ethyl acetate and concentration gave 1.001 g of α-phenethyl alcohol as an oil. Conversion 55%, yield 47.7%.

Provenance & Evidence