Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Acetophenone | HCID 7410 | — |
| Reactant | Aluminum isopropoxide | HCID 11143 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | 1-Phenylethanol | HCID 7409 | 92.3% |
Reaction Steps
Acetophenone (0.601 g) was dissolved in 15 ml of 2-propanol, 2.04 g of aluminum triisopropoxide was added, and the mixture was stirred at 25° C. for 4 hours. After hydrolysis with 1 N hydrochloric acid, the mixture was extracted with ethyl acetate. Concentration gave 0.564 g of an oil, which was analyzed by HPLC (conversion 0.6%, yield 0.4%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06150567 |
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| Source dataset | uspto-grants-2000_11 |
|---|
| ORD ID | ord-6760e1dcf1c44937b0866ccc6db577d0 |
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| Source note | uspto-grants-2000_11 |
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