Water → HCID 178468751, compound

Participants

Reaction Steps

To a mixture of ethyl 4-(bromoacetyl)benzoate (2 g), water (15 ml) and ethanol (14 ml) was added ammonium dithiocarbamate (813 mg) under stirring at room temperature. The stirring was continued for 1 hour at the same temperature and the resulting crystal was collected by filtration. The crystal was added to a mixture of water (15 ml) and ethanol (15 ml), and the mixture was refluxed for 1.5 hours under stirring. The stirring was continued for 30 minutes at 10° C. to give crystal, which were collected by filtration and dried, to give ethyl 4-(2-mercaptothiazol-4-yl)benzoate (1.15 g).

Provenance & Evidence