HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-bromobutanimide → 2-(Bromomethyl)-4-methoxyquinazoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 6-Methylquinoxaline | HCID 242567 | — |
| Reactant | 6-(Bromomethyl)quinoxaline | HCID 10214510 | — |
| Reactant | 4-Methoxy-2-methylquinazoline | HCID 15397066 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | 2-(Bromomethyl)-4-methoxyquinazoline | HCID 17909764 | — |
Reaction Steps
By brominating 2-methyl-4-methoxy-quinazoline [Recl. Trav. Chim. Pays-Bas 76, 401 (1957)] with N-bromosuccinimide in carbon tetrachloride in an analogous manner to the procedure described for the preparation of 6-bromomethylquinoxaline [J. Het. Chem. 11, 595(1974)] from 6-methylquinoxaline there was obtained 2-bromomethyl-4-methoxy-quinazoline as a light yellow solid; MS: 252, 254 (M)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06150526 |
| Source dataset | uspto-grants-2000_11 |
| ORD ID | ord-5cbec01fea49419d9fe1c6a9d1e8ee8e |
| Source note | uspto-grants-2000_11 |