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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1858757Generated: November 1, 2026

Hydrochloric Acid → HCID 22127290, compound

https://huagongshe.com/reaction/1858757

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 22128827HCID 22128827—
SolventMethanolHCID 887—
ProductHCID 22127290HCID 22127290—

Reaction Steps

In an analogous manner to that described in Example 22(l), from tert-butyl 3RS,4SR)-4-[4-(3-benzyloxy-propoxy)-phenyl]-3-(naphthalen-2-yl-acetyl)-piperidine-1-carboxylate by cleavage of the BOC protecting group with hydrogen chloride in methanol there was obtained [(3RS,4SR)-4-[4-(3-benzyloxy-propoxy)-phenyl]-piperidin-3-yl]-2-naphthalen-2-yl-ethanone hydrochloride (1:1) in in the form of colourless crystals; MS: 494 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06150526
Source datasetuspto-grants-2000_11
ORD IDord-9d66a30ca6b640d2aa2d0a54a83565e9
Source noteuspto-grants-2000_11