HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-(Bromomethyl)quinoline--hydrogen bromide (1/1) → HCID 53993008, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-(Bromomethyl)quinoline--hydrogen bromide (1/1) | HCID 21713086 | — |
| Reactant | HCID 54071872 | HCID 54071872 | — |
| Product | HCID 53993008 | HCID 53993008 | — |
Reaction Steps
By alkylating tert-butyl (3RS,4RS)-4-[4-(3-benzyloxy-propoxy)-phenyl]-3-hydroxy-piperidine-1-carboxylate [Example 86(n)] with 7-bromomethyl-quinoline hydrobromide [J.Am.Chem.Soc. 77,1054(1955)] analogously to Example 1(g) there was obtained tert-butyl (3RS,4RS)-4-[4-(3-benzyloxy-propoxy)-phenyl]-3-(quinolin-7-ylmethoxy)-piperidine-1-carboxylate as a colourless oil; MS: 583 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06150526 |
| Source dataset | uspto-grants-2000_11 |
| ORD ID | ord-0f1c2613b5ee45d0b99dd16adb9a3537 |
| Source note | uspto-grants-2000_11 |