2-Naphthalenecarboxylic acid, 1-hydroxy-, methyl ester → Methyl 1-(2-methoxy-ethoxy)-naphthalene-2-carboxylate

Participants

Reaction Steps

By alkylating methyl 1-hydroxy-naphthalene-2-carboxylate analogously to Example 1(g) with 2-bromoethyl methyl ether there was obtained methyl 1-(2-methoxy-ethoxy)-naphthalene-2-carboxylate, which was subsequently converted analogously to Example 5(b)-(c) firstly into [1-(2-methoxy-ethoxy)-naphthalen-2-yl]-methanol and then into 2-chloromethyl-1-(2-methoxy-ethoxy)-naphthalene, which was finally obtained as a beige solid; MS: 250 (M)+.

Provenance & Evidence