1-(2-(pyrrolidin-1-yl)ethyl)-1H-pyrazol-4-amine → [1-(2-Pyrrolidin-1-yl-ethyl)-1H-pyrazol-4-yl]-[8-(4-trifluoromethyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-amine

HRID 185878Notes

Reaction equation

HRID 185878 reaction equation
[Cl:1][c:2]1[n:3][n:4]2[c:5]([c:6](-[c:10]3[cH:11][cH:12][c:13]([C:16]([F:17])([F:18])[F:19])[cH:14][cH:15]3)[cH:7][cH:8][cH:9]2)[n:20]1.[N:21]1([CH2:26][CH2:27][n:28]2[n:29][cH:30][c:31]([NH2:33])[cH:32]2)[CH2:22][CH2:23][CH2:24][CH2:25]1>>[c:2]1([NH:33][c:31]2[cH:30][n:29][n:28]([CH2:27][CH2:26][N:21]3[CH2:22][CH2:23][CH2:24][CH2:25]3)[cH:32]2)[n:3][n:4]2[c:5]([c:6](-[c:10]3[cH:11][cH:12][c:13]([C:16]([F:17])([F:18])[F:19])[cH:14][cH:15]3)[cH:7][cH:8][cH:9]2)[n:20]1

Participants

3

Reactant 2

HCID 621376891-(2-(pyrrolidin-1-yl)ethyl)-1H-pyrazol-4-amineHCID 674813912-Chloro-8-(4-trifluoromethyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridine

Product 1

HCID 68777376[1-(2-Pyrrolidin-1-yl-ethyl)-1H-pyrazol-4-yl]-[8-(4-trifluoromethyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-amine

Sources & evidence

ORD record
ord-782b1520c81b4dbe8126ff294b24966a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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