HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86604496, compound → HCID 22126715, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86604496 | HCID 86604496 | — |
| Catalyst | Zinc bromide | HCID 10421208 | — |
| Product | HCID 22126715 | HCID 22126715 | — |
Reaction Steps
In an analogous manner to that described in Example 125(h), from tert-butyl (3RS,4RS)-4-[2-(3-benzyloxy-propoxy)-pyrimidin-5-yl]-3-(naphthalen-2-ylmethoxy)-piperidine-1-carboxylate by cleavage of the BOC group by means of anhydrous zinc bromide there was obtained 2-(3-benzyloxy-propoxy)-5-[(3RS,4RS)-3-(naphthalen-2-ylmethoxy)-piperidin-4-yl]-pyrimidine in the form of a yellowish gum; MS: 485 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06150526 |
| Source dataset | uspto-grants-2000_11 |
| ORD ID | ord-1fc56118eff54e96986eab901589a9f2 |
| Source note | uspto-grants-2000_11 |