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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1858815Generated: November 1, 2026

HCID 86604496, compound → HCID 22126715, compound

https://huagongshe.com/reaction/1858815

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86604496HCID 86604496—
CatalystZinc bromideHCID 10421208—
ProductHCID 22126715HCID 22126715—

Reaction Steps

In an analogous manner to that described in Example 125(h), from tert-butyl (3RS,4RS)-4-[2-(3-benzyloxy-propoxy)-pyrimidin-5-yl]-3-(naphthalen-2-ylmethoxy)-piperidine-1-carboxylate by cleavage of the BOC group by means of anhydrous zinc bromide there was obtained 2-(3-benzyloxy-propoxy)-5-[(3RS,4RS)-3-(naphthalen-2-ylmethoxy)-piperidin-4-yl]-pyrimidine in the form of a yellowish gum; MS: 485 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06150526
Source datasetuspto-grants-2000_11
ORD IDord-1fc56118eff54e96986eab901589a9f2
Source noteuspto-grants-2000_11