Trifluoroacetic acid → HCID 69646414, compound

Participants

Reaction Steps

In an analogous manner to that described in Example 145(i), from tert-butyl (3'RS,4'RS)-4-(3-benzyloxy-propoxy)-3'-(naphthalen-2-ylmethoxy)-2-oxo-3',4',5',6'-tetrahydro-2H,2'H-[1,4']bipyridine-1'-carboxylate by cleavage of the BOC group by means of trifluoroacetic acid there was obtained (3'RS,4'RS)-4-(3-benzyloxy-propoxy)-3'-(naphthalen-2-ylmethoxy)-1',2',3',4',5',6'-hexahydro-[1,4']bipyridin-2-one trifluoroacetate as a colourless solid; MS: 499 (M+H)+.

Provenance & Evidence