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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1858957Generated: November 3, 2026

4-Phenylpiperidinium chloride → (S)-4-Methyl-2-[4-(4-phenyl-piperidin-1-yl)-benzenesulfonylamino]-pentanoic acid

https://huagongshe.com/reaction/1858957

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Phenylpiperidinium chlorideHCID 82509—
Reactant(S)-2-(4-fluoro-benzenesulfonylamino)-4-methyl-pentanoic acidHCID 6933576—
Product(S)-4-Methyl-2-[4-(4-phenyl-piperidin-1-yl)-benzenesulfonylamino]-pentanoic acidHCID 15432847—

Reaction Steps

In a manner similar to Example 3(b), 4-phenyl-piperidin hydrochloride was condensed with (S)-2-(4-fluoro-benzenesulfonylamino)-4-methyl-pentanoic acid to give the title compound, % C,H,N found: 63.96, 6.96, 6.44.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06153612
Source datasetuspto-grants-2000_11
ORD IDord-288a0d1001c84493b4373ea2487444e4
Source noteuspto-grants-2000_11